Abstract Background Comprehensive environmental risk characterization, encompassing physical, chemical, social, ecological, and lifestyle stressors, necessitates innovative approaches to handle the escalating complexity.This is especially true when considering individual and population-level diversity, where the myriad combinations of real-world ex
Glucocorticoids (GCs), a class of hormones secreted by the adrenal glands, are released into the bloodstream to maintain homeostasis and Accessories modulate responses to various stressors.These hormones function by binding to the widely expressed GC receptor (GR), thereby regulating a wide range of pathophysiological processes, especially in metab
Impaired healing in diabetes affects the resolution of both acute and chronic wounds.The vicious circle between wound chronicity and a deficient control of local infection is the cause that diabetic patients constitute 85% of all non-traumatic lower extremity amputations.From an etiological viewpoint, hyperglycemia is what triggers the onset and pr
Mechanical ventilation is used to improve gas exchange and unload the respiratory muscles allowing for their rest and recovery, which require good synchronization between the patient and the Bishop Rotary V2 MicroAngelo ventilator.Spontaneous respiratory effort is generally preferred because it reduces atelectasis, improves oxygenation, and may pre